MS&T, Process Analytics Co-Op

  • Opportunity Profile:
    • Project Description:
      This project will focus on the adaptation of platform process analytics methods to the Waters PATROL UPLC system and the development of 2-dimensional Titer-SEC method for analysis of upstream samples and an SEC-Titer method for downstream samples. Once developed the methods can be a template for the introduction of alternate characterization and quantitation methods using the 2-dimensional format.
      The adaptation of the current assays will focus on Titer, SEC and Sialic Acid with the goal of optimizing methods with automated processing that do not require sample preparation and are compatible with in-process testing by manufacturing operations. The project will include a standard validation of analytical performance attributes and a comparability of methods.
      The development of 2-dimensional methods will include the evaluation of instrument compatibility and fit between separation modes, the development of and documentation of a protocol and the demonstration of method attributes (accuracy, precision, robustness etc.)
      Year of Individual(s) Requested:  Senior, Masters, PhD
      Major(s): Chemistry, Biochemistry, Chemical Engineering                       
      Location of Assignment(s):  Devens, MA
      Duration of Assignment(s): January 2020 to June 2020 (Co-Op)
      Required skills:
      • Passion for teamwork, immense energy, absolute integrity, and an A+ attitude.
      • Organized with strong written and verbal communication skills
      • Familiarity with laboratory and research practices.
      Bristol-Myers Squibb is looking for highly motivated students to participate in an industry research apprenticeship and co-op program. The ideal candidate will be well-versed in common laboratory practices, skills, and techniques to support scientific experimental design and testing. The apprenticeship and co-op program is designed to introduce the apprentice to the fast-paced, results-driven biotech environment. Research projects will be focused on the development of high-throughput assays for the support of manufacturing process development and characterization.