Upstream Co-Op (Single Chain), Manufacturing Science & Technology Department

  • Opportunity Profile:
      Position: Upstream Co-Op, Manufacturing Science & Technology Department
      Location: Syracuse, NY
      Description: We are seeking a highly motivated student to be part of the upstream laboratory. The successful candidate will design cell culture experiments to understand the formation of the single chain (monomeric) species within the commercial manufacturing process. The individual selected will begin by mapping the single chain and dimeric species intracellularly and in culture supernatant, analysis will be performed on laboratory samples using a modified Western Blotting procedure.  These data will act as an indicator of whether the single chain species forms intracellularly, or is the result of enzymatic reactions in the supernatant.  This project will require method trouble-shooting, therefore experience with SDS-PAGE and Western Blotting is preferred. The co-op will be responsible for collecting, analyzing, and interpreting results with scientific advice and collaboration from a larger team.
      Bristol-Myers Squibb is the industry leader in immuno-oncology with life-saving medicines and a rich clinical portfolio of diverse modalities including monoclonal antibody, antibody drug conjugate, fusion protein, and combination regimes.
      Required skills: 
      • Must be enrolled in school the semester of and/or during the assignment, as well as the semester following the assignment, with a 3.0+ GPA
      • Must be available to work full-time (40 hours/week) from January to July 2020.
      • Demonstrated problem solving ability, interpersonal skills, and oral and written communication skills.
      • Previous work experience in pharmaceuticals, biotechnology, or a related industry preferred.
      • Qualified candidates will have completed sophomore, junior, senior, Masters, or PhD level coursework towards a degree in Chemical/Biochemical Engineering, Biology, Biochemistry, or Related Disciplines
      • Knowledge of bioreactor operation, cell biology, recombinant protein expression, and aseptic technique, as well as demonstrated implementation of such in a professional lab-based setting, protein biochemistry and process development expertise are desired.
      • Preferred experience in SDS-PAGE and Western Blotting.
      • Excellent communication, technical writing, collaboration, and data management skills are required.
      • The demonstrated flexibility to work in a dynamic, project-based environment is essential.
      • Demonstrated application of formal project management, experimental design, statistical analysis, system qualification, equipment maintenance, and problem solving methodologies are helpful.
      • Technical writing ability required, as well as expertise in Microsoft Word, Excel and PowerPoint and the ability to perform statistical data analysis.MS Visio experience preferred.
      Join us.